DOSE ANALYSIS OF BNCT TREATMENT METHOD FOR Rhabdomyosarcoma IN THE HEAD AND NECK REGION BASED ON PHITS CODE

Syamputra, Dhani Nur Indra and Sardjono, Yohannes and Nur'aini, Rida Siti (2018) DOSE ANALYSIS OF BNCT TREATMENT METHOD FOR Rhabdomyosarcoma IN THE HEAD AND NECK REGION BASED ON PHITS CODE. S1 thesis, FMIPA.

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Abstract

The objectives of this research are: (1) to know the optimum Boron dose for treating rhabdomyosarcoma in the head and neck region, and (2) to know the effective irradiation time to treat rhabdomyosarcoma in the head and neck region. This research was using Particle and Heavy Ions Transport code System (PHITS) to simulate neutron source and BNCT doses. Neutron source used was Kartini Reactor. The simulation was done by creating geometry of cancer tissue and head and neck region. Boron concentration variance in this research was 30, 35, 40, 45, and 50 μg/g tissue. The output of PHITS were neutron flux and neutron dose. The neutron flux value was used to acquire alpha dose, proton dose, and gamma dose inside tissues. The result of this research shows that: (1) the optimum boron dose for treating Rhabdomyosarcoma in the head and neck region is 50 μg/g tissue, and (2) the effective irradiation time to cure Rhabdomyosarcoma in the head and neck region is 7 hours and 4 minutes, which is acquired by the boron concentration of 50 μg/g tissue. The higher the boron concentration level, the higher the dose rate, the quicker irradiation time, and lesser radiation dose received by healthy tissues.

Item Type: Thesis (S1)
Uncontrolled Keywords: boron dose, rhabdomyosarcoma, BNCT, Kartini Reactor, PHITS
Subjects: Matematika dan Ilmu Pengetahuan Alam > Fisika
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Jurusan Pendidikan Fisika > Fisika
Depositing User: Admin Fisika FMIPA
Date Deposited: 23 Jul 2018 04:13
Last Modified: 30 Jan 2019 16:42
URI: http://eprints.uny.ac.id/id/eprint/57745

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