Sri , Atun, Ph.D SOME PHENOLIC COMPOUNDS FROM STEM BARK OF MELINJO (GNETUM GNEMON) AND THEIR ACTIVITY TEST AS ANTIOXIDANT AND UV-B PROTECTION. [Experiment/Research]
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Abstract
Isolation and structure elucidation of three phenolic compounds, namely 3,4-dimethoxychlorogenic acid (1), resveratrol (2), and 3-methoxyresveratrol (3) from stem bark of Melinjo (Gnetum gnemon) had been done. The isolation of those compounds was carried out by chromatographyc method and structure elucidation was performed by interpretation of spectroscopic data, including UV, IR, 1H and 13C NMR 1D and 2D, and FABMS. The result of this study showed that activity each compounds as radical hydroxyl scavenger of 3,4-dimethoxychlorogenic acid (3), resveratrol (2), and 3-methoxyresveratrol (3), with an IC50 523,7; 45,17; and 60,12; g/ml respectively. Each compound showed significant activity as UV-B protection. Activity test as UV-B protection showed that resveratrol and methoxyresveratrol have maximum protections (SPF 8,03 and 12,34 respectively), and 3,4-dimethoxychlorogenic acid has minimum protection (SPF 2,55), each compounds on 50 g/ml. Key word : melinjo; Gnetum gnemon; natural antioxidant; UV-B protection FMIPA, 2007 (PEND. KIMIA)
| Item Type: | Experiment/Research |
|---|---|
| Subjects: | Matematika dan Ilmu Pengetahuan Alam > Kimia |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Jurusan Pendidikan Kimia > Kimia |
| Depositing User: | Jurusan Kimia |
| Date Deposited: | 12 Sep 2012 15:05 |
| Last Modified: | 12 Sep 2012 15:05 |
| URI: | http://eprints.uny.ac.id/id/eprint/5442 |
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