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<> <http://xmlns.com/foaf/0.1/primaryTopic> <http://eprints.uny.ac.id/id/eprint/24247> .
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<http://eprints.uny.ac.id/id/eprint/24247> <http://purl.org/dc/terms/title> "UJI AKTIVITAS ANTIMUTAGENIK EKSTRAK METANOL RIMPANG TUMBUHAN KUNCI PEPET (KAEMPHERA ROTUNDA) BERDASARKAN JUMLAH SEL ERITROSIT BERMIKRONUKLEUS (MNPCE) SERTA ISOLASI \r\nDAN IDENTIFIKASI KOMPONENNYA"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://eprints.uny.ac.id/id/eprint/24247> <http://purl.org/ontology/bibo/abstract> "Tujuan dari penelitian ini adalah untuk menguji aktivitas antimutagenik  rimpang tumbuhan kunci pepet (Kaemphera rotunda), melakukan isolasi serta identifikasi struktur molekul komponen penyusunnya. Metode yang digunakan adalah melalui penelitian di laboratorium. Ekstraksi dari rimpang kunci pepet dilakukan secara maserasi dengan pelarut metanol. Ekstrak yang diperoleh dikeringkan dan diuji aktivitas antimutagenik secara invivo menggunakan mencit jantan galur Balb-c yang berusia 6-7 minggu. Uji aktivitas antimutagenik dilakukan dengan menghitung jumlah sel eritrosit polikromatik bermikronukleus (MNPCE) dari mencit akibat induksi senyawa penyebab mutasi (siklofosfamid) dibandingkan terhadap mencit kontrol dan eksperimen. Dosis ekstrak sampel yang digunakan  300 dan 600 mg/Kg bb. Isolasi dan identifikasi struktur ekstrak metanol kunci pepet dilakukan dengan metode kromatografi vakum cair, kromatografi gravitasi dengan pelarut yang sesuai. Sedangkan identifikasi struktur dilakukan secara spektroskopi UV, IR, dan NMR satu dan dua dimensi. Hasil penelitian menunjukkan persentase aktivitas antimutagenik ekstrak metanol kunci pepet pada dosis 300 mg/kg bb 80%. Dari penelitian ini juga dapat diisolasi dan ditentukan strukturnya tiga senyawa flavanon, yaitu 4’-hidroksi-8-metoksi-flavanon, 6- hidroksi-8-metoksi-flavanon, dan  4’, 8-dihidroksi-flavanon."^^<http://www.w3.org/2001/XMLSchema#string> .
<http://eprints.uny.ac.id/id/eprint/24247> <http://purl.org/dc/terms/date> "2012" .
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